4,6-Difluoropyrimidine → 4-Fluoro-6-(4-iodo-2,5-dimethyl-imidazol-1-yl)-pyrimidine
反応式
[I:1][C:2]1[N:3]=[C:4]([CH3:8])[NH:5][C:6]=1[CH3:7].[F:9][C:10]1[CH:15]=[C:14](F)[N:13]=[CH:12][N:11]=1>>[F:9][C:10]1[CH:15]=[C:14]([N:5]2[C:6]([CH3:7])=[C:2]([I:1])[N:3]=[C:4]2[CH3:8])[N:13]=[CH:12][N:11]=1参加物
3
実験手順
The title compound, white cristalline solid, MS: m/e=340.2, 342.1 (M+H+) was prepared in accordance with the general method of example 1b from 4-iodo-2,5-dimethyl-1H-imidazole and 4,6-difluoropyrimidine.
出典と根拠
- ORDレコード
- ord-bcd8c98099b0455b82c5083429cca93f
- 出典データセット
- uspto-grants-2012_12
- 特許番号
- US08334287B2
反応ノート
読み込み中…