3-Methylphenylacetylene → 2-ethyl-5-(2-methyl-4-m-tolylethynyl-imidazol-1-yl)-2H-pyridazin-3-one

HRID 2194452ノート

反応式

HRID 2194452 の反応式
[CH2:1]([N:3]1[C:8](=[O:9])[CH:7]=[C:6]([N:10]2[CH:14]=[C:13](I)[N:12]=[C:11]2[CH3:16])[CH:5]=[N:4]1)[CH3:2].[C:17]([C:19]1[CH:24]=[CH:23][CH:22]=[C:21]([CH3:25])[CH:20]=1)#[CH:18]>>[CH2:1]([N:3]1[C:8](=[O:9])[CH:7]=[C:6]([N:10]2[CH:14]=[C:13]([C:18]#[C:17][C:19]3[CH:20]=[C:21]([CH3:25])[CH:22]=[CH:23][CH:24]=3)[N:12]=[C:11]2[CH3:16])[CH:5]=[N:4]1)[CH3:2]

参加物

3

反応物 2

HCID 1366003-MethylphenylacetyleneHCID 668657362-ethyl-5-(4-iodo-2-methyl-imidazol-1-yl)-2H-pyridazin-3-one

生成物 1

HCID 498728622-ethyl-5-(2-methyl-4-m-tolylethynyl-imidazol-1-yl)-2H-pyridazin-3-one

実験手順

The title compound, light brown crystalline solid, MS: m/e=319.1 (M+), was prepared in accordance with the general method of example 21a from 2-ethyl-5-(4-iodo-2-methyl-imidazol-1-yl)-2H-pyridazin-3-one and 1-ethynyl-3-methyl-benzene.

出典と根拠

ORDレコード
ord-8fe4b779d7c24d78adaa0be409f91f2e
出典データセット
uspto-grants-2012_12
特許番号
US08334287B2

反応ノート

読み込み中…