Potassium Carbonate → 4-[4-(5-Bromo-3-methyl-pyridin-2-yl)-2-(R)-methyl-piperazin-1-yl]-2-chloro-6-(4-fluoro-phenyl)-pyrimidine
反応式
[Cl:1][C:2]1[N:7]=[C:6](Cl)[CH:5]=[C:4]([C:9]2[CH:14]=[CH:13][C:12]([F:15])=[CH:11][CH:10]=2)[N:3]=1.[Br:16][C:17]1[CH:18]=[C:19]([CH3:30])[C:20]([N:23]2[CH2:28][CH2:27][NH:26][C@H:25]([CH3:29])[CH2:24]2)=[N:21][CH:22]=1.C([O-])([O-])=O.[K+].[K+]>CC(N(C)C)=O>[Br:16][C:17]1[CH:18]=[C:19]([CH3:30])[C:20]([N:23]2[CH2:28][CH2:27][N:26]([C:6]3[CH:5]=[C:4]([C:9]4[CH:14]=[CH:13][C:12]([F:15])=[CH:11][CH:10]=4)[N:3]=[C:2]([Cl:1])[N:7]=3)[C@H:25]([CH3:29])[CH2:24]2)=[N:21][CH:22]=1参加物
5
