2-Methoxy-n-(3-(1-(2-(methylamino)ethyl)piperidin-4-yl)phenyl)benzamide → 2-Methoxy-n-(2-nitro-4-(1,2,3,6-tetrahydropyridin-4-yl)phenyl)benzamide
反応式
[CH3:1][O:2][C:3]1[CH:27]=[CH:26][CH:25]=[CH:24][C:4]=1[C:5](NC1C=CC=C(C2CCN(CCNC)CC2)C=1)=[O:6].[NH2:28][C:29]1[CH:34]=[CH:33][C:32]([C:35]2[CH2:40][CH2:39][N:38](C(OC(C)(C)C)=O)[CH2:37][CH:36]=2)=[CH:31][C:30]=1[N+:48]([O-:50])=[O:49]>>[CH3:1][O:2][C:3]1[CH:27]=[CH:26][CH:25]=[CH:24][C:4]=1[C:5]([NH:28][C:29]1[CH:34]=[CH:33][C:32]([C:35]2[CH2:40][CH2:39][NH:38][CH2:37][CH:36]=2)=[CH:31][C:30]=1[N+:48]([O-:50])=[O:49])=[O:6]参加物
3
実験手順
The title compound 202 (1.04 g, 2.22 mmol, 71%) was prepared following the procedures described for the synthesis of 192 (scheme 33, Example 36, steps 5 and 6) using 201 (1.00 g, 3.13 mmol) in place of 190. LRMS (ESI): calc. 353.1, found 411.3 (MH)+.
出典と根拠
- ORDレコード
- ord-494cc6c5c36b41ce9114254ebf87b5d7