Stannous Chloride → 4-(2-Amino-4-methylphenoxy)phenol

反応式

[CH3:1][C:2]1[CH:15]=[CH:14][C:5]([O:6][C:7]2[CH:12]=[CH:11][C:10]([OH:13])=[CH:9][CH:8]=2)=[C:4]([N+:16]([O-])=O)[CH:3]=1.Cl[Sn]Cl>>[NH2:16][C:4]1[CH:3]=[C:2]([CH3:1])[CH:15]=[CH:14][C:5]=1[O:6][C:7]1[CH:8]=[CH:9][C:10]([OH:13])=[CH:11][CH:12]=1

参加物

反応物 2

HCID 24479Stannous Chloride

HCID 608710474-(4-Methyl-2-nitrophenoxy)phenol

生成物 1

HCID 668083884-(2-Amino-4-methylphenoxy)phenol収率 86%

実験手順

The product from Example 122a (1.89 g, 7.71 mmol) was reduced with SnCl2 following the procedure from Example 1f giving the title compound as a white solid (1.42 g, 86%).

出典と根拠

ORDレコード: ord-2c1f8de5de874545a6812918479a130c
出典データセット: uspto-grants-2012_12
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US08338605B2

反応ノート

読み込み中…