Hydrochloric Acid → (3-Bromo-1,2-oxazol-5-yl)methanamine hydrochloride
反応式
[Br:1][C:2]1[CH:6]=[C:5]([CH2:7][NH:8]S(C(C)(C)C)=O)[O:4][N:3]=1.[ClH:15].O1CCOCC1>CO>[ClH:15].[Br:1][C:2]1[CH:6]=[C:5]([CH2:7][NH2:8])[O:4][N:3]=1参加物
5
実験手順
To a solution of 2-methyl-propane-2-sulfinic acid (3-bromo-isoxazol-5-ylmethyl)-amide (128 mg, 0.455 mmol) in MeOH (5 mL) was added a 4 M solution of HCl in dioxane (0.350 mL, 1.40 mmol) dropwise. After 2 hours and 10 minutes, the reaction mixture was concentrated in vacuo to afford the title compound which was used without further purification.
後処理
- concentration10 minutes, the reaction mixture was concentrated in vacuo
出典と根拠
- ORDレコード
- ord-091cc70a435a467da2271ca2eb14866d
- 出典データセット
- uspto-grants-2012_12
- 特許番号
- US08338610B2
反応ノート
読み込み中…