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Sodium borohydride → 9-Hydroxymethyl-9,10-dihydro-9,10-methanoanthracene
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Sodium borohydride | HCID 4311764 | — |
| 反応物 | 9,10-Dihydro-9,10-methanoanthracene-9-carboxaldehyde | HCID 12404141 | — |
| 溶媒 | Methanol | HCID 887 | — |
| 溶媒 | Water | HCID 962 | — |
| 生成物 | 9-Hydroxymethyl-9,10-dihydro-9,10-methanoanthracene | HCID 13069082 | — |
反応手順
A solution of 9-formyl-9,10-dihydro-9,10-methanoanthracene (200 mg) and sodium borohydride (60 mg) in methanol (5 ml) was stirred at room temperature for 30 minutes. The reaction mixture was diluted with water and extracted with ethyl acetate. The ethyl acetate layer was washed with water, dried over anhydrous sodium sulfate and evaporated to dryness to give 9-hydroxymethyl-9,10-dihydro-9,10-methanoanthracene. M.P. 165°-166° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04358620 |
| 出典データセット | uspto-grants-1982_11 |
| ORD ID | ord-b4b5c81661214b2ab17ab7850509a70e |
| 出典メモ | uspto-grants-1982_11 |