関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Potassium cyanate | HCID 11378442 | — |
| 反応物 | 9-Tosyloxymethyl-9,10-dihydro-9,10-methanoanthracene | HCID 20519959 | — |
| 溶媒 | Water | HCID 962 | — |
| 溶媒 | Dimethylformamide | HCID 6228 | — |
| 生成物 | (9,10-Dihydro-9,10-methano-9-anthryl)acetonitrile | HCID 13069087 | — |
反応手順
A mixture of 9-tosyloxymethyl-9,10-dihydro-9,10-methanoanthracene (188 mg) and potassium cyanate (40 mg) in dimethylformamide (2 ml) was heated at 150° C. for 7 hours. The reaction mixture was diluted with water and extracted with benzene. The benzene extract was washed with water, dried over anhydrous sodium sulfate and evaporated to dryness to give crude crystals of (9,10-dihydro-9,10-methano-9-anthryl)acetonitrile, which was recrystallized from isopropanol to give pure crystals. M.P. 130°-131° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US04358620 |
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| 出典データセット | uspto-grants-1982_11 |
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| ORD ID | ord-94d72a7e56384f7589e3e478ca5d4832 |
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| 出典メモ | uspto-grants-1982_11 |
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