4-(Dimethylamino)Benzaldehyde → 4-[4-(2-Chlorophenyl)-2,2-dimethyl-2,5-dihydro-1,3-oxazol-5-yl]-N,N-dimethylaniline

HRID 2198937ノート

反応式

HRID 2198937 の反応式
[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[C:8]1[C:9]([CH3:12])([CH3:11])[N:10]=1.[CH3:13][N:14]([CH3:23])[C:15]1[CH:22]=[CH:21][C:18]([CH:19]=[O:20])=[CH:17][CH:16]=1>>[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[C:8]1[CH:19]([C:18]2[CH:21]=[CH:22][C:15]([N:14]([CH3:23])[CH3:13])=[CH:16][CH:17]=2)[O:20][C:9]([CH3:11])([CH3:12])[N:10]=1

参加物

3

反応物 2

HCID 74794-(Dimethylamino)BenzaldehydeHCID 205177763-(2-Chlorophenyl)-2,2-dimethyl-2H-azirene

生成物 1

HCID 30614364-[4-(2-Chlorophenyl)-2,2-dimethyl-2,5-dihydro-1,3-oxazol-5-yl]-N,N-dimethylaniline

実験手順

According to the procedure described in Example 1, from 30 g of 3-(o-chlorophenyl)-2,2-dimethyl-2H-azirine and 24 g of p-(dimethylamino)benzaldehyde there was obtained 4-(o-chlorophenyl)-5-[p-(dimethylamino)phenyl]-2,2-dimethyl-3-oxazoline which melted at 72.5°-73.5° C. after drying for 4 hours at 35° C. and 13 Torr.

出典と根拠

ORDレコード
ord-295340b0227c4833abaf214057833146
出典データセット
uspto-grants-1982_11
特許番号
US04360530

反応ノート

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