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Methyl 5-bromopyridine-3-carboxylate → Methyl 5-(4-ethylphenyl)pyridine-3-carboxylate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Methyl 5-bromopyridine-3-carboxylate | HCID 699336 | — |
| 反応物 | Boronic acid, (4-ethylphenyl)- | HCID 2734352 | — |
| 生成物 | Methyl 5-(4-ethylphenyl)pyridine-3-carboxylate | HCID 58002322 | — |
反応手順
According to General Method 3A, 32 g (148 mmol) of methyl 5-bromonicotinate and 27 g (178 mmol, 1.2 eq.) of 4-ethylphenylboronic acid were reacted. Yield: 24 g (64% of theory)
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08202862B2 |
| 出典データセット | uspto-grants-2012_06 |
| ORD ID | ord-b6e49e33a74f4231b8f1b4a940e0c780 |
| 出典メモ | uspto-grants-2012_06 |