Benzyl Bromide → Methyl 2-(4-(benzyloxy)-3-bromophenyl)acetate

HRID 2200390ノート

反応式

HRID 2200390 の反応式
[Br:1][C:2]1[CH:3]=[C:4]([CH2:9][C:10]([O:12][CH3:13])=[O:11])[CH:5]=[CH:6][C:7]=1[OH:8].C(=O)([O-])[O-].[K+].[K+].[CH2:20](Br)[C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1>CC(C)=O>[Br:1][C:2]1[CH:3]=[C:4]([CH2:9][C:10]([O:12][CH3:13])=[O:11])[CH:5]=[CH:6][C:7]=1[O:8][CH2:20][C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1

参加物

5

反応物 3

HCID 7498Benzyl BromideHCID 11430Potassium CarbonateHCID 10634081Methyl 2-(3-bromo-4-hydroxyphenyl)acetate

生成物 1

HCID 56605342Methyl 2-(4-(benzyloxy)-3-bromophenyl)acetate

試薬・触媒・溶媒 1

HCID 180Acetone溶媒

実験手順

Compound 10 (12.3 g) was dissolved in 100 mL acetone and 7.6 g of potassium carbonate was added. 8.6 g of benzyl bromide was added with stirring. The solid was removed by suction filtration and the liquid was evaporated to product 11.

後処理

  1. customThe solid was removed by suction filtration
  2. customthe liquid was evaporated to product 11

出典と根拠

ORDレコード
ord-d183db3ee6454f69b0c850e9b2968b79
出典データセット
uspto-grants-2016_06
特許番号
US09359372B2

反応ノート

読み込み中…