Chloroacetone → HCID 90402786、化合物
反応式
[C:1]([CH2:3][C:4]1[CH:5]=[C:6]([CH:10]=[CH:11][CH:12]=1)[C:7]([NH2:9])=[O:8])#[N:2].Cl[CH2:14][C:15](=O)[CH3:16]>>[CH3:16][C:15]1[N:9]=[C:7]([C:6]2[CH:5]=[C:4]([CH2:3][C:1]#[N:2])[CH:12]=[CH:11][CH:10]=2)[O:8][CH:14]=1参加物
3
実験手順
A solution of 3-(cyanomethyl)benzamide (200 mg, 1.25 mmol) in 1-chloropropan-2-one (2 mL) was microwave irradiated at 120 for 20 min in a sealed tube. The mixture was concentrated to give crude product (110 mg), which was directly used to the next reaction without purification. LCMS MH+ 199.
後処理
- concentrationThe mixture was concentrated
出典と根拠
- ORDレコード
- ord-a67079d97cd44a5fa76841c3a5d6db89
- 出典データセット
- uspto-grants-2016_06
- 特許番号
- US09359359B2
反応ノート
読み込み中…