関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Hydroquinone | HCID 785 | — |
| 反応物 | 1,3-Butadiene | HCID 7845 | — |
| 反応物 | 1,2-Dimethoxy-4-(2-nitrovinyl)benzene | HCID 709688 | — |
| 溶媒 | Toluene | HCID 1140 | — |
| 生成物 | (+/-)-trans-1,2-DI methoxy-4-(2-nitrocyclohex-4-enyl)benzene | HCID 53874256 | — |
反応手順
50.0 g of 3,4-dimethoxy-ω-nitrostyrene (compound J1), and 1.0 g (9.1 mmol) of hydroquinone are suspended in 200 ml of abs. toluene and treated at −70° C. with 55.0 g (1.02 mol) of liquid 1,3-butadiene. The mixture is stirred at 160° C. for 6 days in an autoclave and then cooled. Some of the solvent is removed on a rotary evaporator, and the resulting precipitate is filtered off with suction and recrystallized in ethanol. M.p.: 113.5-115.5° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US08202880B2 |
|---|
| 出典データセット | uspto-grants-2012_06 |
|---|
| ORD ID | ord-b017856a109d4402a420d2b2018985e4 |
|---|
| 出典メモ | uspto-grants-2012_06 |
|---|
