Hydrochloric Acid → (R)-2-amino-2-cyclopropylacetamide hydrochloride
反応式
[NH2:1][C:2](=[O:15])[C@H:3]([NH:7]C(=O)OC(C)(C)C)[CH:4]1[CH2:6][CH2:5]1.[ClH:16]>O1CCOCC1>[ClH:16].[NH2:7][C@H:3]([CH:4]1[CH2:6][CH2:5]1)[C:2]([NH2:1])=[O:15]参加物
4
実験手順
A solution of (R)-tert-butyl 2-amino-1-cyclopropyl-2-oxoethylcarbamate (300 mg, 1.40 mmol) in 4N HCl in dioxane (8 mL) was stirred at room temperature for 20 min. It was then concentrated in vacuo to give (R)-2-amino-2-cyclopropylacetamide hydrochloride (225 mg).
後処理
- concentrationIt was then concentrated in vacuo
出典と根拠
- ORDレコード
- ord-d47152a3947f4140940e6fe980514e92
- 出典データセット
- uspto-grants-2016_06
- 特許番号
- US09359375B2
反応ノート
読み込み中…