Tin tetrachloride → (E)-1-methoxy-8-methyl-10-pentyl-3,4,5,6,9,10-hexahydroazecin-2(1H)-one
反応式
[CH2:1]=[C:2]([CH:4]1[CH2:9][CH2:8][CH2:7][CH2:6][C:5]1=[O:10])[CH3:3].[CH2:11]([O:13][N:14]=[CH:15][CH2:16][CH2:17][CH2:18][CH2:19][CH3:20])C.Cl[Sn](Cl)(Cl)Cl>ClCCCl>[CH3:11][O:13][N:14]1[CH:15]([CH2:16][CH2:17][CH2:18][CH2:19][CH3:20])[CH2:3][C:2]([CH3:1])=[CH:4][CH2:9][CH2:8][CH2:7][CH2:6][C:5]1=[O:10]参加物
5
実験手順
Following the general procedure as described in Example 17, 2-(prop-1-en-2-yl)cyclohexanone (0.88 g, 6.38 mmol), hexanal O-ethyl oxime (0.99 g, 7.65 mmol), and SnCl4 (1.66 g, 6.38 mmol) in 1,2-dichloroethane (65 ml) were reacted to give the title product as a colorless liquid (1.00 g, 59% yield). E isomer>98%.
後処理
- customwere reacted
出典と根拠
- ORDレコード
- ord-4cf36810dec34a169919c08b278a0534
- 出典データセット
- uspto-grants-2016_06
- 特許番号
- US09371262B2
反応ノート
読み込み中…