Potassium Carbonate → 4-(1,3-Dimethyl-1H-pyrazol-4-ylmethyl)-3'-(3-trifluoromethoxyphenyl)-3,4,5,6-tetrahydro-2H-[1,2']bipyrazine

反応式

[F:1][C:2]([F:14])([F:13])[O:3][C:4]1[CH:5]=[C:6](B(O)O)[CH:7]=[CH:8][CH:9]=1.Cl[C:16]1[C:17]([N:22]2[CH2:27][CH2:26][N:25]([CH2:28][C:29]3[C:30]([CH3:35])=[N:31][N:32]([CH3:34])[CH:33]=3)[CH2:24][CH2:23]2)=[N:18][CH:19]=[CH:20][N:21]=1.CN(C)C(=O)C.C(=O)([O-])[O-].[K+].[K+]>C1C=CC([P]([Pd]([P](C2C=CC=CC=2)(C2C=CC=CC=2)C2C=CC=CC=2)([P](C2C=CC=CC=2)(C2C=CC=CC=2)C2C=CC=CC=2)[P](C2C=CC=CC=2)(C2C=CC=CC=2)C2C=CC=CC=2)(C2C=CC=CC=2)C2C=CC=CC=2)=CC=1.O>[CH3:34][N:32]1[CH:33]=[C:29]([CH2:28][N:25]2[CH2:24][CH2:23][N:22]([C:17]3[C:16]([C:6]4[CH:7]=[CH:8][CH:9]=[C:4]([O:3][C:2]([F:14])([F:13])[F:1])[CH:5]=4)=[N:21][CH:20]=[CH:19][N:18]=3)[CH2:27][CH2:26]2)[C:30]([CH3:35])=[N:31]1