Hydrogen chloride-ethyl acetate → oxan-3-ylhydrazine dihydrochloride
反応式
[O:1]1[CH2:6][CH2:5][CH2:4][CH:3]([NH:7][NH:8]C(OC(C)(C)C)=O)[CH2:2]1.C(OCC)(=O)C.[ClH:22]>>[ClH:22].[ClH:22].[O:1]1[CH2:6][CH2:5][CH2:4][CH:3]([NH:7][NH2:8])[CH2:2]1参加物
3
実験手順
tert-Butyl 2-(tetrahydro-2H-pyran-3-yl)hydrazinecarboxylate (3.65 g) was dissolved in 4N hydrogen chloride-ethyl acetate solution (85 mL) under ice-cooling, and the solution was stirred overnight, at room temperature. The reaction mixture was concentrated under reduced pressure to give the title compound (2.40 g).
後処理
- temperaturecooling
- concentrationThe reaction mixture was concentrated under reduced pressure
出典と根拠
- ORDレコード
- ord-396cdd7087e6472b96c0ae7e734f85e7
- 出典データセット
- uspto-grants-2016_06
- 特許番号
- US09371320B2
反応ノート
読み込み中…