(5-(Trifluoromethyl)pyridin-3-yl)methanol → (5-(Trifluoromethyl)pyridin-3-yl)methyl methanesulfonate
反応式
[CH3:1][S:2]([O:5][CH2:6][C:7]1[CH:8]=[N:9][CH:10]=N[CH:12]=1)(=[O:4])=[O:3].[F:13][C:14]([F:24])([F:23])[C:15]1C=C(CO)C=NC=1>>[CH3:1][S:2]([O:5][CH2:6][C:7]1[CH:8]=[N:9][CH:10]=[C:15]([C:14]([F:24])([F:23])[F:13])[CH:12]=1)(=[O:4])=[O:3]参加物
3
実験手順
(5-(Trifluoromethyl)pyridin-3-yl)methyl methanesulfonate was prepared in a similar manner as used to prepare pyrimidin-5-ylmethyl methanesulfonate using (5-(trifluoromethyl)pyridin-3-yl)methanol instead of pyrimidin-5-ylmethanol. LCMS-ESI+ (m/z): [M+H]+ calc'd for C8H8F3NO3S: 256.02; found: 256.06.
出典と根拠
- ORDレコード
- ord-1cec04665a6643018501ed9b4825ea9c
- 出典データセット
- uspto-grants-2016_06
- 特許番号
- US09376392B2
反応ノート
読み込み中…