AE-646/11813021 → Cubane-1-carboxylic acid
反応式
C1[O:5][C:4]2([C:9]3(Br)[CH:10]4[CH:13]5[CH:6]2[CH:7]2C(=O)[C:12]5(Br)[CH:11]4[CH:8]23)[O:3]C1>[OH-].[K+]>[C:9]12([C:4]([OH:3])=[O:5])[CH:8]3[CH:7]4[CH:12]5[CH:11]3[CH:10]1[CH:13]5[CH:6]24参加物
3
実験手順
Cubanecarboxylic acid (53578-15-7) (33) is obtained from (32) by the method of Eaton and Cole, by refluxing the ketal in 25% aqueous KOH overnight. Extraction with methylene chloride, drying over magnesium sulfate, stripping the solvent, and recrystallization from pentane yields (33), mp 154°-155° C.; λmax (CCl4) 5.91μ; proton NMR (CCl4, ppm τ): -2.2(1H, s) , and 5.6-6.2(7H, m).
後処理
- extractionExtraction with methylene chloride
- dry with materialdrying over magnesium sulfate
- customthe solvent, and recrystallization from pentane
出典と根拠
- ORDレコード
- ord-c34a073fbaf949b88af1c3323fe69644
- 出典データセット
- uspto-grants-1995_10
- 特許番号
- US05455072
反応ノート
読み込み中…