化工社化工社 化学情報印刷レポート · 研究参考用
Phthalic Acid → 4-[3-(2-Carboxybenzoylamino)propylthio]pyridine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Phthalic Acid | HCID 1017 | — |
| 反応物 | 4-(3-Aminopropylthio)pyridine | HCID 15227695 | — |
| 溶媒 | Dichloromethane | HCID 6344 | — |
| 生成物 | 4-[3-(2-Carboxybenzoylamino)propylthio]pyridine | HCID 19079108 | 92.3% |
反応手順
A solution of 340 mg (2.02 mmol) of 4-(3-aminopropylthio)pyridine and 738 mg (4.98 mmol) of anhydrous phthalic acid in 5 ml of methylene chloride was stirred at room temperature for 30 minutes. The resulting crystals were filtered and dried to obtain 590 mg of the desired compound (92.3%, colorless powder), mp: 151.0°-153.3° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05457106 |
| 出典データセット | uspto-grants-1995_10 |
| ORD ID | ord-7a3ff4c3da6d4209a50b11a20382f399 |
| 出典メモ | uspto-grants-1995_10 |