Hydrogen Peroxide → Catechol

HRID 22104

反応式

HRID 22104 の反応式
[C:1]1([OH:7])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[O:8]1[CH2:13][CH2:12][O:11]CC1.OO>C1COC(N2C(=O)NC(=O)C(F)=C2)C1.O>[C:1]1([CH:6]=[CH:5][C:4]([OH:8])=[CH:3][CH:2]=1)[OH:7].[C:13]1([C:12](=[CH:6][CH:1]=[CH:2][CH:3]=1)[OH:11])[OH:8]

参加物

7

反応物 3

HCID 784Hydrogen PeroxideHCID 996PhenolHCID 312751,4-Dioxane

生成物 2

HCID 289CatecholHCID 785Hydroquinone

試薬・触媒・溶媒 2

HCID 5386Tegafur触媒HCID 962Water溶媒

反応条件

温度
70 °C

実験手順

A stirrer, a cooler and a temperature indicator were provided to a four-necked flask having an internal volume of 200 ml; to this flask, 13.0 g of phenol, 4.0 g of 1,4-dioxane, 6.0 g of water and 1.3 g of TS-1 catalyst, prepared according to the above described procedure, were added, and heated to 70° C. by an oil bath. After the temperature of the mixture reached 70° C., 3.0 g of 31 weight % of hydrogen peroxide was added dropwise using a quantitative pump over 2 hours, and stirred further for 20 minutes after the addition. The reaction solution was analyzed by liquid chromatography, and the yields of hydroquinone and catechol were calculated. The results are shown in Table 1.

後処理

  1. customA stirrer, a cooler and a temperature indicator were provided to a four-necked flask
  2. additionwere added
  3. customreached 70° C.
  4. customover 2 hours
  5. additionafter the addition

出典と根拠

ORDレコード
ord-d186916510c642398ce38322f1c0400d
出典データセット
uspto-grants-1995_06
特許番号
US05426244

関連ノート

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