2-Phenylthiophene → 5-Bromo-2-fluoro-1-(5-phenyl-2-thienylmethyl)benzene

HRID 221091

反応式

HRID 221091 の反応式
[C:1]1([C:7]2[S:8][CH:9]=[CH:10][CH:11]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[Br:12][C:13]1[CH:14]=[CH:15][C:16]([F:21])=[C:17]([CH:20]=1)[CH:18]=O>>[Br:12][C:13]1[CH:14]=[CH:15][C:16]([F:21])=[C:17]([CH2:18][C:9]2[S:8][C:7]([C:1]3[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=3)=[CH:11][CH:10]=2)[CH:20]=1

参加物

3

反応物 2

HCID 699992-PhenylthiopheneHCID 7363275-Bromo-2-fluorobenzaldehyde

生成物 1

HCID 666082205-Bromo-2-fluoro-1-(5-phenyl-2-thienylmethyl)benzene

実験手順

2-Phenylthiophene and 5-bromo-2-fluorobenzaldehyde were treated in a manner similar to Reference Example 7 to give the target compound. APCI-Mass m/Z 347/349 (M+H).

後処理

  1. customto give the target compound

出典と根拠

ORDレコード
ord-c7b37103c6094a1390df5fcc9478efb6
出典データセット
uspto-grants-2012_06
特許番号
US08202984B2

関連ノート

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