2-Phenylthiophene → 2-(5-Bromo-2-methylbenzyl)-5-phenylthiophene

反応式

[C:1]1([C:7]2[S:8][CH:9]=[CH:10][CH:11]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[Br:12][C:13]1[CH:14]=[CH:15][C:16]([CH3:22])=[C:17]([CH:21]=1)[C:18](O)=O>>[Br:12][C:13]1[CH:14]=[CH:15][C:16]([CH3:22])=[C:17]([CH2:18][C:9]2[S:8][C:7]([C:1]3[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=3)=[CH:11][CH:10]=2)[CH:21]=1

参加物

反応物 2

HCID 699992-Phenylthiophene

HCID 3460045-Bromo-2-methylbenzoic acid

生成物 1

HCID 666083062-(5-Bromo-2-methylbenzyl)-5-phenylthiophene

実験手順

2-Phenylthiophene and 5-bromo-2-methylbenzoic acid obtained in Reference Example 4-(1) were treated in a manner similar to Reference Example 5 to give the target compound. APCI-Mass m/Z 343/345 (M+H).

後処理

addition4-(1) were treated in a manner similar to Reference Example 5
customto give the target compound

出典と根拠

ORDレコード: ord-a0b4703a02474cab9a595999e67115eb
出典データセット: uspto-grants-2012_06
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US08202984B2

反応ノート

読み込み中…

参加物