5-Bromo-2-methylbenzoic acid → 5-Bromo-1-(5-(3-chlorophenyl)-2-thienylmethyl)-2-methylbenzene
反応式
[Cl:1][C:2]1[CH:3]=[C:4]([C:8]2[S:9][CH:10]=[CH:11][CH:12]=2)[CH:5]=[CH:6][CH:7]=1.[Br:13][C:14]1[CH:15]=[CH:16][C:17]([CH3:23])=[C:18]([CH:22]=1)[C:19](O)=O>>[Br:13][C:14]1[CH:15]=[CH:16][C:17]([CH3:23])=[C:18]([CH2:19][C:10]2[S:9][C:8]([C:4]3[CH:5]=[CH:6][CH:7]=[C:2]([Cl:1])[CH:3]=3)=[CH:12][CH:11]=2)[CH:22]=1参加物
3
実験手順
2-(3-Chlorophenyl)thiophene obtained in Reference Example 85-(1) and 5-bromo-2-methylbenzoic acid obtained in Reference Example 4-(1) were treated in a manner similar to Reference Example 5 to give the target compound as colorless oil.
後処理
- addition4-(1) were treated in a manner similar to Reference Example 5
出典と根拠
- ORDレコード
- ord-d294767297444f3083076ed6ebd9bc6e
- 出典データセット
- uspto-grants-2012_06
- 特許番号
- US08202984B2
反応ノート
読み込み中…