4-Bromo-2-methylbenzoic acid → HCID 66607523、化合物

HRID 221131ノート

反応式

HRID 221131 の反応式
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2[S:10][CH:11]=[CH:12][CH:13]=2)=[CH:5][CH:4]=1.[Br:14][C:15]1[CH:23]=[CH:22][C:18]([C:19](O)=O)=[C:17]([CH3:24])[CH:16]=1>>[Br:14][C:15]1[CH:23]=[CH:22][C:18]([CH3:19])=[C:17]([CH2:24][C:11]2[S:10][C:9]([C:6]3[CH:5]=[CH:4][C:3]([O:2][CH3:1])=[CH:8][CH:7]=3)=[CH:13][CH:12]=2)[CH:16]=1

参加物

3

反応物 2

HCID 995704-Bromo-2-methylbenzoic acidHCID 27694252-(4-methoxyphenyl)thiophene

生成物 1

HCID 66607523HCID 66607523、化合物

実験手順

The above 2-(4-methoxyphenyl)thiophene and 4-bromo-2-methylbenzoic acid obtained in Reference Example 4-(1) were treated in a manner similar to Reference Example 5 to give 5-bromo-1-(5-(4-methoxyphenyl)-2-thienylmethyl)-2-methylbenzene as a pale yellow solid. APCI-Mass m/Z 373/375 (M+H).

後処理

  1. addition4-(1) were treated in a manner similar to Reference Example 5

出典と根拠

ORDレコード
ord-8fda82240ea94a9b9fc8f2f2c68e001c
出典データセット
uspto-grants-2012_06
特許番号
US08202984B2

反応ノート

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