化工社化工社 化学情報印刷レポート · 研究参考用
4-Fluorobenzoyl chloride → 4-Fluoro-N-(2,2,4,6,7-pentamethyl-3-(4-methylphenyl)-2,3-dihydro-1-benzofuran-5-yl]benzamide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 4-Fluorobenzoyl chloride | HCID 67879 | — |
| 反応物 | 2,2,4,6,7-Pentamethyl-3-(4-methylphenyl)-2,3-dihydro-1-benzofuran-5-amine | HCID 10685309 | — |
| 溶媒 | Ethyl acetate hexane | HCID 21226206 | — |
| 生成物 | 4-Fluoro-N-(2,2,4,6,7-pentamethyl-3-(4-methylphenyl)-2,3-dihydro-1-benzofuran-5-yl]benzamide | HCID 10202094 | 43% |
反応手順
By using 2,2,4,6,7-pentamethyl-3-(4-methylphenyl)-2,3-dihydro-1-benzofuran-5-amine and 4-fluorobenzoyl chloride, the title compound was synthesized according to Example 1b. Yield: 43%. Melting point: 148-120° C. (Ethyl acetate-hexane).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07101867B2 |
| 出典データセット | uspto-grants-2006_09 |
| ORD ID | ord-e350ff223b42422fac48a66fdec0b149 |
| 出典メモ | uspto-grants-2006_09 |