N-[4-(2-Chloroethyl)-2,5-dimethylphenyl]acetamide → N-(4-{2-[4-(1H-Indazol-3-YL)-piperazin-1-YL]-ethyl}-2.5-dimethyl-phenyl)-acetamide

HRID 2211918

反応式

HRID 2211918 の反応式
Cl[CH2:2][CH2:3][C:4]1[C:9]([CH3:10])=[CH:8][C:7]([NH:11][C:12](=[O:14])[CH3:13])=[C:6]([CH3:15])[CH:5]=1.Cl.[N:17]1([C:23]2[C:31]3[C:26](=[CH:27][CH:28]=[CH:29][CH:30]=3)[NH:25][N:24]=2)[CH2:22][CH2:21][NH:20][CH2:19][CH2:18]1>>[NH:25]1[C:26]2[C:31](=[CH:30][CH:29]=[CH:28][CH:27]=2)[C:23]([N:17]2[CH2:18][CH2:19][N:20]([CH2:2][CH2:3][C:4]3[C:9]([CH3:10])=[CH:8][C:7]([NH:11][C:12](=[O:14])[CH3:13])=[C:6]([CH3:15])[CH:5]=3)[CH2:21][CH2:22]2)=[N:24]1

参加物

3

反応物 2

HCID 21963433N-[4-(2-Chloroethyl)-2,5-dimethylphenyl]acetamideHCID 219634343-(Piperazin-1-yl)-1H-indazole hydrochloride

生成物 1

HCID 21963196N-(4-{2-[4-(1H-Indazol-3-YL)-piperazin-1-YL]-ethyl}-2.5-dimethyl-phenyl)-acetamide

実験手順

N-[4-(2-Chloro-ethyl)-2,5-dimethyl-phenyl]-acetamide (0.142 g, 0.631 mmol) was reacted with 3-piperazin-1-yl-1H-indazole hydrochloride (0.226 g, 0.946 mmol) according to the method outlined in Example 501.

出典と根拠

ORDレコード
ord-cf021d051ce44bdc8dbf5e0733046c52
出典データセット
uspto-grants-2006_09
特許番号
US07101886B2

関連ノート

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