2,5-Dichlorobenzeneacetic acid → N-{[4-(3,4-Dichlorobenzyl)morpholin-2-yl]methyl}2-(2,5-dichlorophenyl)acetamide
反応式
[Cl:1][C:2]1[CH:3]=[C:4]([CH:14]=[CH:15][C:16]=1[Cl:17])[CH2:5][N:6]1[CH2:11][CH2:10][O:9][CH:8]([CH2:12][NH2:13])[CH2:7]1.[Cl:18][C:19]1[CH:24]=[CH:23][C:22]([Cl:25])=[CH:21][C:20]=1[CH2:26][C:27](O)=[O:28]>>[Cl:1][C:2]1[CH:3]=[C:4]([CH:14]=[CH:15][C:16]=1[Cl:17])[CH2:5][N:6]1[CH2:11][CH2:10][O:9][CH:8]([CH2:12][NH:13][C:27](=[O:28])[CH2:26][C:20]2[CH:21]=[C:22]([Cl:25])[CH:23]=[CH:24][C:19]=2[Cl:18])[CH2:7]1参加物
3
実験手順
Example 13 was prepared in an analogous manner to Example 4 using a mixture of Intermediate 1 (0.055 g) and (2,5-dichlorophenyl)acetic acid (0.041 g) to give the title compound (0.025 g).
後処理
- customExample 13 was prepared in an analogous manner to Example 4 using