化工社化工社 化学情報印刷レポート · 研究参考用
(alpha,alpha,alpha-Trifluoro-4-tolyl)acetic acid → N-{[4-(3,4-Dichlorobenzyl)morpholin-2-yl]methyl}-2-[4-(trifluoromethyl)phenyl]acetamide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | (alpha,alpha,alpha-Trifluoro-4-tolyl)acetic acid | HCID 118342 | — |
| 反応物 | [4-(3,4-Dichlorobenzyl)morpholin-2-yl]methylamine | HCID 10308229 | — |
| 生成物 | N-{[4-(3,4-Dichlorobenzyl)morpholin-2-yl]methyl}-2-[4-(trifluoromethyl)phenyl]acetamide | HCID 21962841 | 16.3% |
反応手順
Example 14 was prepared in an analogous manner to Example 1 using a mixture of Intermediate 1 (0.055 g) and [4-(trifluoromethyl)phenyl]acetic acid (0.041 g) to give thetitle compound (0.015 g).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07101882B2 |
| 出典データセット | uspto-grants-2006_09 |
| ORD ID | ord-d84e619c9e6849a4a23b0af635468afd |
| 出典メモ | uspto-grants-2006_09 |