2-Fluoro-4-(trifluoromethyl)benzaldehyde → 2-Fluoro-4-(trifluoromethyl)cinnamic acid
反応式
CS(OC1C=CC(/C=[CH:13]/[C:14]([OH:16])=[O:15])=CC=1)(=O)=O.[F:17][C:18]1[CH:25]=[C:24]([C:26]([F:29])([F:28])[F:27])[CH:23]=[CH:22][C:19]=1[CH:20]=O.C(C1C=CC(OS(C)(=O)=O)=CC=1)=O>>[F:17][C:18]1[CH:25]=[C:24]([C:26]([F:29])([F:28])[F:27])[CH:23]=[CH:22][C:19]=1/[CH:20]=[CH:13]/[C:14]([OH:16])=[O:15]参加物
4
実験手順
5.12 g of (E)-2-Fluoro-4-(trifluoromethyl)cinnamic acid were synthesized as described for (E)-3-(4-(methanesulfonyloxy)phenyl)acrylic acid using 2-fluoro-4-trifluoromethylbenzaldehyde (commercially available from Aldrich) instead of methanesulfonic acid 4-formylphenyl ester.
出典と根拠
- ORDレコード
- ord-240fde7c4bb840ab8df31cec2fff2f65
- 出典データセット
- uspto-grants-2006_09
- 特許番号
- US07101898B2
反応ノート
読み込み中…