化工社化工社 化学情報印刷レポート · 研究参考用
Water → 2-(3-Nitrophenyl)-2-oxoethyl acetate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Water | HCID 962 | — |
| 反応物 | 2-Bromo-1-(3-nitrophenyl)ethan-1-one | HCID 75213 | — |
| 反応物 | Sodium Acetate | HCID 517045 | — |
| 溶媒 | Methyl Ethyl Ketone | HCID 6569 | — |
| 生成物 | 2-(3-Nitrophenyl)-2-oxoethyl acetate | HCID 13173800 | 87.5% |
反応手順
2-Bromo-1-(3-nitrophenyl)ethanone (25 g) was dissolved in methylethyl ketone (150 mL). NaOAc (12.5 g) was added and the mixture stirred for 48 hours. Water (100 mL) was added and the reaction mixture extracted with DCM. The DCM layer was dried over Na2SO4 and concentrated to give the title compound (20 g, 87%).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08207167B2 |
| 出典データセット | uspto-grants-2012_06 |
| ORD ID | ord-125495b67b2042a49067997dd3748cf8 |
| 出典メモ | uspto-grants-2012_06 |