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3-Nitroquinolin-4-amine → HCID 178419901、化合物
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 3-Nitroquinolin-4-amine | HCID 280005 | — |
| 反応物 | 3,4-Diaminoquinoline | HCID 1514289 | — |
| 反応物 | 3-Nitro-1,5-naphthyridin-4-amine | HCID 13122788 | — |
| 反応物 | [1,5]Naphthyridine-3,4-diamine | HCID 22172703 | — |
| 生成物 | HCID 178419901 | HCID 178419901 | — |
| 生成物 | 1h-Imidazo[4,5-c][1,5]naphthyridine | HCID 178420735 | — |
反応手順
In steps (2) and (3) of Reaction Scheme II, a 3-nitroquinolin-4-amine or 3-nitro[1,5]naphthyridin-4-amine of Formula XXVI is first reduced to a quinoline-3,4-diamine or [1,5]naphthyridine-3,4-diamine of Formula XXVII, which is then treated with a halogen-substituted carboxylic acid equivalent to provide a 1H-imidazo[4,5-c]quinoline or 1H-imidazo[4,5-c][1,5]naphthyridine of Formula XXVIII. Steps (2) and (3) of Reaction Scheme II can be carried out according to the methods described in steps (3) and (4) of Reaction Scheme I.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08207162B2 |
| 出典データセット | uspto-grants-2012_06 |
| ORD ID | ord-02a80e51d15b486b8383b42cbf6a6c96 |
| 出典メモ | uspto-grants-2012_06 |