Isopentadecan-1-ol → 13-methyltetradecanal

HRID 2215874ノート

反応式

HRID 2215874 の反応式
[CH3:1][CH:2]([CH3:16])[CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][OH:15]>ClCCl>[CH3:1][CH:2]([CH3:16])[CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH:14]=[O:15]

参加物

3

反応物 1

HCID 94094Isopentadecan-1-ol

生成物 1

HCID 1108550713-methyltetradecanal収率 51%

試薬・触媒・溶媒 1

HCID 6344Dichloromethane溶媒2 回

実験手順

Chloro-chromic pyridine (161.6 g, 0.75 mole) and 450 ml dichloromethane were added to a flask. With stirring, 150 ml dichloromethane solution of 13-methyl-1-tetradecanol (114 g, 0.50 mole) was slowly added to the flask and stirring continued for 1.5 hours at room temperature. Let the mixture stand and separate into two phases. Decant upper phase and wash the remainder with 100 ml diethyl ether. Combine all liquid and wash sequentially with saturated NaCl, 10% HCl, and saturated NaCl solution with 5% NaHCO3. Desiccate with anhydrous CaCl2 and remove solvent by evaporation to yield 13-methyl-tetradecanaldehyde (57.6 g, yield rate 51%).

後処理

  1. stirringstirring
  2. customseparate into two phases
  3. customDecant upper phase
  4. washwash the remainder with 100 ml diethyl ether
  5. washCombine all liquid and wash sequentially with saturated NaCl, 10% HCl, and saturated NaCl solution with 5% NaHCO3
  6. customDesiccate with anhydrous CaCl2 and remove solvent
  7. customby evaporation

出典と根拠

ORDレコード
ord-d903c0b942024688b9098a2f5c07d6cf
出典データセット
uspto-grants-2006_09
特許番号
US07109364B2

反応ノート

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