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HRID 2216378作成日：2026年10月27日

2-Benzyl-3-iodo-6-[(3R,4R)-3-hydroxy-4-methoxypyrrolidin-1-yl]pyridine → 2-[[1-[2-Benzyl-6-[(3R,4R)-3-hydroxy-4-methoxypyrrolidin-1-yl]-3-pyridyl]ethynylcyclohexyl]amino]ethanol

https://huagongshe.com/reaction/2216378

反応式

関与物質

役割名称HCID仕込み量
反応物2-Benzyl-3-iodo-6-[(3R,4R)-3-hydroxy-4-methoxypyrrolidin-1-yl]pyridineHCID 11384307—
反応物2-[(1-Ethynylcyclohexyl)amino]ethanolHCID 14792886—
生成物2-[[1-[2-Benzyl-6-[(3R,4R)-3-hydroxy-4-methoxypyrrolidin-1-yl]-3-pyridyl]ethynylcyclohexyl]amino]ethanolHCID 10204226—

反応手順

This was synthesized in the same manner as in Example 6 except that 2-benzyl-3-iodo-6-[(3R,4R)-3-hydroxy-4-methoxypyrrolidin-1-yl]pyridine (Production Example 1) and 2-[(1-ethynylcyclohexyl)amino]ethanol (Production Example 20) were used.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US07112593B2
出典データセットuspto-grants-2006_09
ORD IDord-dd582e3741784cdf8a05d5b030dabe01
出典メモuspto-grants-2006_09