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1-Methylpiperazine → 5-Amino-2-(4-methylpiperazin-1-yl)benzonitrile
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 1-Methylpiperazine | HCID 53167 | — |
| 反応物 | 2-Chloro-5-nitrobenzonitrile | HCID 85504 | — |
| 生成物 | 5-Amino-2-(4-methylpiperazin-1-yl)benzonitrile | HCID 17609581 | 62.5% |
反応手順
By the reaction and treatment in the same manner as in Starting Material Synthetic Example 4 using 2-chloro-5-nitrobenzonitrile (15 g) and methylpiperazine (9.8 g), the title compound (11.1 g) was obtained. melting point: 45-46° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07112594B2 |
| 出典データセット | uspto-grants-2006_09 |
| ORD ID | ord-58fcb8b3c4f747289de79d546576b89c |
| 出典メモ | uspto-grants-2006_09 |