化工社化工社 化学情報印刷レポート · 研究参考用
Benzo(b)thiophene-2-carboxylic acid → N-[3-cyano-4-(4-methylpiperazin-1-yl)phenyl]benzo[b]thiophene-2-carboxamide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Benzo(b)thiophene-2-carboxylic acid | HCID 95864 | — |
| 反応物 | 5-Amino-2-(4-methylpiperazin-1-yl)benzonitrile | HCID 17609581 | — |
| 生成物 | N-[3-cyano-4-(4-methylpiperazin-1-yl)phenyl]benzo[b]thiophene-2-carboxamide | HCID 21942320 | 36.4% |
反応手順
By the reaction and treatment in the same manner as in Example 6 using benzo[b]thiophene-2-carboxylic acid (1.3 g) and 5-amino-2-(4-methylpiperazin-1-yl)benzonitrile (1.6 g), the title compound (1.0 g) was obtained. melting point: 263-264° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07112594B2 |
| 出典データセット | uspto-grants-2006_09 |
| ORD ID | ord-bd29e0bf0edf4d8c8ad09f2b0e801b45 |
| 出典メモ | uspto-grants-2006_09 |