Boron trifluoride etherate → HCID 10309887、化合物
反応式
O[C:2]([C:14]1[CH:19]=[CH:18][C:17]([N:20]([CH3:30])[S:21]([C:24]2[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=2)(=[O:23])=[O:22])=[CH:16][CH:15]=1)([C:5]1[N:6]([CH2:10][CH2:11][O:12][CH3:13])[CH:7]=[CH:8][CH:9]=1)[CH2:3][CH3:4].C([SiH](CC)CC)C.B(F)(F)F.CCOCC>>[CH3:13][O:12][CH2:11][CH2:10][N:6]1[CH:7]=[CH:8][CH:9]=[C:5]1[CH:2]([C:14]1[CH:19]=[CH:18][C:17]([N:20]([CH3:30])[S:21]([C:24]2[CH:25]=[CH:26][CH:27]=[CH:28][CH:29]=2)(=[O:22])=[O:23])=[CH:16][CH:15]=1)[CH2:3][CH3:4]参加物
4
実験手順
The title compound was prepared from N-(4-{1-hydroxy-1-[1-(2-methoxyethyl)-1H-pyrrol-2-yl]-propyl}-phenyl)-N-methyl-benzenesulfonamide (Example 2) using triethylsilane and boron trifluoride diethyl etherate as described in Example 88 of co-pending application Ser. No. 10/354,922, entitled “Arylsulfonamidobenzylic Compounds” and provided below as Preparative Example B.