Boron trifluoride etherate → HCID 10216587、化合物
反応式
O[C:2]([C:15]1[CH:20]=[CH:19][C:18]([N:21]([CH3:31])[S:22]([C:25]2[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=2)(=[O:24])=[O:23])=[CH:17][CH:16]=1)([C:6]1[N:7]([CH2:11][CH2:12][O:13][CH3:14])[CH:8]=[CH:9][CH:10]=1)[CH2:3][CH2:4][CH3:5].C([SiH](CC)CC)C.B(F)(F)F.CCOCC>>[CH3:14][O:13][CH2:12][CH2:11][N:7]1[CH:8]=[CH:9][CH:10]=[C:6]1[CH:2]([C:15]1[CH:16]=[CH:17][C:18]([N:21]([CH3:31])[S:22]([C:25]2[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=2)(=[O:24])=[O:23])=[CH:19][CH:20]=1)[CH2:3][CH2:4][CH3:5]参加物
4
実験手順
The title compound was prepared from N-(4-{1-hydroxy-1-[1-(2-methoxyethyl)-1H-pyrrol-2-yl]-butyl}-phenyl)-N-methyl-benzenesulfonamide (Example 3) using triethylsilane and boron trifluoride diethyl etherate as described in Example 88 of co-pending application Ser. No. 10/354,922, entitled “Arylsulfonamidobenzylic Compounds” and provided below as Preparative Example B.
後処理
- customprovided below as Preparative Example B