化工社化工社 化学情報印刷レポート · 研究参考用
Trifluoroacetic acid → (4R)-4,8-Dimethylnonanoic acid
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Trifluoroacetic acid | HCID 6422 | — |
| 反応物 | tert-butyl (4R)-4,8-dimethylnonanoate | HCID 71406104 | — |
| 溶媒 | Dichloromethane | HCID 6344 | — |
| 生成物 | (4R)-4,8-Dimethylnonanoic acid | HCID 71351570 | — |
反応手順
(4R)-4,8-dimethyl nonanoic acid t-butyl ester in 25 mL CH2Cl2 at 0° C. was treated with TFA (6 mL). The mixture was allowed to reach ambient temperature and stir overnight. The solvent was removed by rotary evaporation, and the mixture was purified by silica gel chromatography (95/5 hexane/EtOAc) to give 0.962 g (4R)-4,8-dimethyl nonanoic acid. m/z 185 (M−).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07112610B2 |
| 出典データセット | uspto-grants-2006_09 |
| ORD ID | ord-e656345034e8472ca3eea80aa20356e3 |
| 出典メモ | uspto-grants-2006_09 |