2-Hydrazinobenzoxazole → 1-(2-Pyridyl)-1-propanone-1-(1,3-benzoxazol-2-yl)hydrazone
反応式
[C:1]([C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][N:6]=1)(=O)[CH2:2][CH3:3].[NH:11]([C:13]1[O:14][C:15]2[CH:21]=[CH:20][CH:19]=[CH:18][C:16]=2[N:17]=1)[NH2:12]>CO.C(O)(=O)C>[O:14]1[C:15]2[CH:21]=[CH:20][CH:19]=[CH:18][C:16]=2[N:17]=[C:13]1[NH:11][N:12]=[C:1]([C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][N:6]=1)[CH2:2][CH3:3]参加物
5
実験手順
A mixture of 2-propionyl pyridine (0.60 g, 4.42 mmol) and 2-hydrazinobenzoxazole (0.60 g 4.02 mmol) in 25 ml of methanol is refluxed for 24 hours after the addition of 6 drops of glacial acetic acid. The reaction mixture is stored over night in the refrigerator at approximately 5° C. The precipitate is filtered and recrystallized from diisopropyl ether. Yield: 0.68 g (64% of theory).