4-Bromo-2-(Trifluoromethoxy)Benzene-1-Sulfonyl Chloride → 4-bromo-N-(2-morpholin-4-yl-ethyl)-2-trifluoromethoxy-benzene sulfonamide
反応式
[Br:1][C:2]1[CH:7]=[CH:6][C:5]([S:8]([NH:11][CH2:12][CH2:13][N:14]2[CH2:19][CH2:18][O:17][CH2:16][CH2:15]2)(=[O:10])=[O:9])=[C:4](C)[CH:3]=1.BrC1C=CC(S(Cl)(=O)=O)=C([O:32][C:33]([F:36])([F:35])[F:34])C=1>>[Br:1][C:2]1[CH:7]=[CH:6][C:5]([S:8]([NH:11][CH2:12][CH2:13][N:14]2[CH2:19][CH2:18][O:17][CH2:16][CH2:15]2)(=[O:10])=[O:9])=[C:4]([O:32][C:33]([F:36])([F:35])[F:34])[CH:3]=1参加物
3
実験手順
The title compound was prepared in the same manner as described for 4-bromo-2-methyl-N-(2-morpholin-4-yl-ethyl)benzene sulfonamide, replacing 4-bromo-2-methyl-benzene sulfonyl chloride with 4-bromo-2-trifluoromethoxybenzene sulfonyl chloride. 1H-NMR (DMSO-d6) δ 7.88 to 7.77 (m, 4H), 3.43 (t, J=4.2 Hz, 4H), 2.99 to 2.97 (broad s, 2H), 2.29 to 2.20 (m, 6H); MS LC-MS [M+H]+=433 & 435, RT=2.03 min.
出典と根拠
- ORDレコード
- ord-e2ec11ffde9143af841a37865b352109
- 出典データセット