[3-(Benzo[b]thiophen-4-yloxy)-5-methyl-hexyl]-benzyl-methyl-amine → [3-(Benzo[b]thiophen-4-yloxy)-heptyl]-benzyl-methyl-amine

HRID 2220354ノート

反応式

HRID 2220354 の反応式
[S:1]1[CH:5]=[CH:4][C:3]2[C:6]([O:10][CH:11]([CH2:23]C(C)C)[CH2:12][CH2:13][N:14]([CH2:16][C:17]3[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=3)[CH3:15])=[CH:7][CH:8]=[CH:9][C:2]1=2.[CH2:27](N(C)CCC(O)CCCC)[C:28]1C=CC=C[CH:29]=1>>[S:1]1[CH:5]=[CH:4][C:3]2[C:6]([O:10][CH:11]([CH2:23][CH2:27][CH2:28][CH3:29])[CH2:12][CH2:13][N:14]([CH2:16][C:17]3[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=3)[CH3:15])=[CH:7][CH:8]=[CH:9][C:2]1=2

参加物

3

反応物 2

HCID 10316919[3-(Benzo[b]thiophen-4-yloxy)-5-methyl-hexyl]-benzyl-methyl-amineHCID 179819331-(Benzyl-methyl-amino)-heptan-3-ol

生成物 1

HCID 9976265[3-(Benzo[b]thiophen-4-yloxy)-heptyl]-benzyl-methyl-amine

実験手順

Using a method similar to that for [3-(Benzo[b]thiophen-4-yloxy)-5-methyl-hexyl]-benzyl-methyl-amine, 1-(benzyl-methyl-amino)-heptan-3-ol affords the title compound: mass spectrum (ion spray) m/z=368 (M+1); 1H NMR (CDCl3) δ 8 7.45-7.41 (m, 2H), 7.29-7.19 (m, 7H), 6.80 (d, 1H), 4.56-4.51 (m, 1H), 3.47 (s, 2H), 2.55 (t, 2H), 2.20 (s, 3H), 2.01-1.91 (m, 2H), 1.90-1.63 (m, 3H), 1.45-1.29 (m, 4H), 0.89 (t, 3H).

出典と根拠

ORDレコード
ord-99713532e68149f9a007461096d92a57
出典データセット
uspto-grants-2008_08
特許番号
US07417064B2

反応ノート

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