Hydrochloric Acid → HCID 22873880、化合物
反応式
[C@@H:1]1([N:10](C)[C:11](=O)OC(C)(C)C)[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[CH2:3][CH2:2]1.[ClH:19]>CO>[ClH:19].[CH3:11][NH:10][C@@H:1]1[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[CH2:3][CH2:2]1参加物
4
実験手順
To a solution of tert-butyl(1S)-2,3-dihydro-1H-inden-1-yl(methyl)carbamate (1.84 g, 7.44 mmol) in MeOH (50.0 mL) under an atmosphere of nitrogen was added hydrochloric acid (6.00 mL, 72.4 mmol) and the mixture was stirred overnight. The reaction was concentrated in vacuo to afford the title compound as a white solid without further purification (1.35 g, 99%). LC/MS: Rt=0.85 min, ES+ 148 (AA standard).
後処理
- concentrationThe reaction was concentrated in vacuo
出典と根拠
- ORDレコード
- ord-0ee560d9a07c461da12c71826d236174
- 出典データセット
- uspto-grants-2012_06
- 特許番号
- US08207177B2
反応ノート
読み込み中…