化工社化工社 化学情報印刷レポート · 研究参考用
2-Azabicyclo(2.2.2)octane → 2-Aza-bicyclo[2.2.2]octane-2-carboxylic acid [4-methoxy-7-(tetrahydro-pyran-4-yl)-benzothiazol-2-yl]-amide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2-Azabicyclo(2.2.2)octane | HCID 9236 | — |
| 反応物 | Phenyl chloroformate | HCID 15891 | — |
| 反応物 | 4-Methoxy-7-(tetrahydro-pyran-4-yl)-benzothiazol-2-yl-amine | HCID 22015735 | — |
| 生成物 | 2-Aza-bicyclo[2.2.2]octane-2-carboxylic acid [4-methoxy-7-(tetrahydro-pyran-4-yl)-benzothiazol-2-yl]-amide | HCID 11384069 | — |
反応手順
Using 4-methoxy-7-(tetrahydro-pyran-4-yl)-benzothiazol-2-ylamine, phenyl chloroformate and 2-aza-bicyclo[2.2.2]octane, the title compound was prepared as off-white crystals (53% yield). MS: m/e=402(M+H+), mp 237-239° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07371748B2 |
| 出典データセット | uspto-grants-2008_05 |
| ORD ID | ord-0de5a3b0151c44e7b1a777f62343ef92 |
| 出典メモ | uspto-grants-2008_05 |