関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Ammonia | HCID 222 | — |
| 反応物 | Benzoic acid, 3-methyl-2-nitro-, methyl ester | HCID 79621 | — |
| 溶媒 | Methanol | HCID 887 | — |
| 生成物 | 3-Methyl-2-nitrobenzamide | HCID 3271371 | — |
反応手順
Methyl 3-methyl-2-nitrobenzoate (10.02 g, 51.3 mmol) was added to a 7N solution of ammonia in methanol (50 mL) and the mixture was heated at 100° C. in a Fisher-Porter tube for 3 hours. The solution was then cooled, concentrated and triturated with dichloromethane to give the title compound of Step A as a white solid (14 g).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US07375232B2 |
|---|
| 出典データセット | uspto-grants-2008_05 |
|---|
| ORD ID | ord-056bd7b515214900876475b49e95e6cf |
|---|
| 出典メモ | uspto-grants-2008_05 |
|---|
