C([O:4][CH2:5][C:6]1[CH:7]=[C:8]([CH:41]=[C:42]([CH2:44][O:45]C(=O)C)[CH:43]=1)[O:9][CH2:10][CH2:11][C:12]1([CH2:18][CH2:19][N:20]2[CH2:25][CH2:24][CH:23]([N:26]([C:34]3[CH:39]=[CH:38][C:37]([CH3:40])=[CH:36][CH:35]=3)[C:27]([C:29]3[O:30][CH:31]=[CH:32][CH:33]=3)=[O:28])[CH2:22][CH2:21]2)[CH2:17][CH2:16][CH2:15][CH2:14][CH2:13]1)(=O)C.C(=O)([O-])[O-].[K+].[K+]>CO>[OH:4][CH2:5][C:6]1[CH:7]=[C:8]([CH:41]=[C:42]([CH2:44][OH:45])[CH:43]=1)[O:9][CH2:10][CH2:11][C:12]1([CH2:18][CH2:19][N:20]2[CH2:25][CH2:24][CH:23]([N:26]([C:34]3[CH:39]=[CH:38][C:37]([CH3:40])=[CH:36][CH:35]=3)[C:27]([C:29]3[O:30][CH:31]=[CH:32][CH:33]=3)=[O:28])[CH2:22][CH2:21]2)[CH2:17][CH2:16][CH2:15][CH2:14][CH2:13]1To a solution of N-[1-[2-[1-[2-[3,5-bis(acetoxymethyl)phenoxy]ethyl]cyclohexyl]ethyl]piperidin-4-yl]-N-(p-tolyl)-2-furancarboxamide (276 mg) dissolved in methanol (4 mL) was added potassium carbonate (11 mg). The solution was stirred at room temperature for 2 hours. The reaction solution was concentrated under reduced pressure. Saturated aqueous sodium bicarbonate solution was added to the solution, and it was extracted with chloroform-ethanol (80:20). The organic layer was dried over anhydrous magnesium sulfate, and filtered. The filtrate was then concentrated under reduced pressure to give the title compound (228 mg).
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