化工社化工社 化学情報印刷レポート · 研究参考用
3-amino-N,N-dimethylbenzene-1-sulfonamide → 7-Difluoromethyl-5-(4-trifluoromethyl-phenyl)-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid(3-dimethylsulfamoyl-phenyl)-amide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 3-amino-N,N-dimethylbenzene-1-sulfonamide | HCID 235520 | — |
| 反応物 | 7-Difluoromethyl-5-(4-trifluoromethyl-phenyl)-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid | HCID 66650268 | — |
| 生成物 | 7-Difluoromethyl-5-(4-trifluoromethyl-phenyl)-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid(3-dimethylsulfamoyl-phenyl)-amide | HCID 11504811 | — |
反応手順
The title compound was prepared from 7-difluoromethyl-5-(4-trifluoromethyl-phenyl)-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid (example C.1) and 3-amino-N,N-dimethyl-benzenesulfonamide [CAS 6274-18-6; commercially available] according to general procedure II. Light yellow solid. MS (ISP) 540.4 [(M+H)+]; mp 197° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07378417B2 |
| 出典データセット | uspto-grants-2008_05 |
| ORD ID | ord-8e6588fc509840509425290382db29b9 |
| 出典メモ | uspto-grants-2008_05 |