Benzoic acid, 4-(phenylmethoxy)-, 1-(trifluoromethyl)heptyl ester → 1,1,1-Trifluoro-2-octyl 4-hydroxybenzoate

HRID 2226070ノート

反応式

HRID 2226070 の反応式
C([O:8][C:9]1[CH:28]=[CH:27][C:12]([C:13]([O:15][CH:16]([CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH3:26])[C:17]([F:20])([F:19])[F:18])=[O:14])=[CH:11][CH:10]=1)C1C=CC=CC=1>C(O)C.[Pd].[C]>[OH:8][C:9]1[CH:10]=[CH:11][C:12]([C:13]([O:15][CH:16]([CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH3:26])[C:17]([F:18])([F:19])[F:20])=[O:14])=[CH:27][CH:28]=1

参加物

4

反応物 1

HCID 14549213Benzoic acid, 4-(phenylmethoxy)-, 1-(trifluoromethyl)heptyl ester

生成物 1

HCID 145492151,1,1-Trifluoro-2-octyl 4-hydroxybenzoate収率 100.8%

試薬・触媒・溶媒 2

HCID 178418390HCID 178418390、化合物触媒HCID 702Ethanol溶媒

実験手順

In 15 ml of ethanol, 1.8 g of 1,1,1-trifluoro-2-octyl 4-benzyloxybenzoate prepared in the reaction step [3] mentioned above was dissolved and 0.3 g of Pd-carbon was further added. The mixture was stirred at an ambient temperature for a whole day and night under a hydrogen gas atmosphere. After the Pd-carbon was filtered off, the solvent was distilled off at a reduced pressure to obtain 1.4 g of the objective compound.

後処理

  1. dissolutionabove was dissolved
  2. filtrationAfter the Pd-carbon was filtered off
  3. distillationthe solvent was distilled off at a reduced pressure

出典と根拠

ORDレコード
ord-d3d4769e90b74297900523f17fe6a69c
出典データセット
uspto-grants-1994_09
特許番号
US05346648

反応ノート

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