Water → 4-[2-(4-(4-Methyl-3-pentenyl)-3-cyclohexenyl)ethyl]phenol

HRID 2227103ノート

反応式

HRID 2227103 の反応式
[CH3:1][C:2]([CH3:22])=[CH:3][CH2:4][CH2:5][C:6]1[CH2:11][CH2:10][CH:9]([CH2:12][CH2:13][C:14]2[CH:19]=[CH:18][C:17]([O:20]C)=[CH:16][CH:15]=2)[CH2:8][CH:7]=1.B(Br)(Br)Br.O>ClCCl>[CH3:1][C:2]([CH3:22])=[CH:3][CH2:4][CH2:5][C:6]1[CH2:11][CH2:10][CH:9]([CH2:12][CH2:13][C:14]2[CH:15]=[CH:16][C:17]([OH:20])=[CH:18][CH:19]=2)[CH2:8][CH:7]=1

参加物

5

反応物 3

HCID 962WaterHCID 25134Boron tribromideHCID 184718172-(4-(4-Methyl-3-pentenyl)-3-cyclohexenyl)ethyl-4-methoxybenzene

生成物 1

HCID 184718234-[2-(4-(4-Methyl-3-pentenyl)-3-cyclohexenyl)ethyl]phenol

試薬・触媒・溶媒 1

HCID 6344Dichloromethane溶媒

実験手順

To a solution of anisole 2F (R=4-Methyl-3-pentenyl) (6 g) in dichloromethane (100 mL) and cooled in an ice bath is added a 1M solution of boron tribromide (3.4 mL). The solution is stirred for one hour, then poured into water. The reaction mixture is extracted with dichloromethane and dried over magnesium sulfate. The solution is concentrated in vacuo. The product is recrystallized from hexane.

後処理

  1. extractionThe reaction mixture is extracted with dichloromethane
  2. dry with materialdried over magnesium sulfate
  3. concentrationThe solution is concentrated in vacuo
  4. customThe product is recrystallized from hexane

出典と根拠

ORDレコード
ord-cd9462bf4bf542ca9fff7f6eea480cb0
出典データセット
uspto-grants-2002_07
特許番号
US06413448B1

反応ノート

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