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HRID 2227654作成日：2026年10月27日

Sodium Hydroxide → 1-Methyl-2-[N-(4-amidinophenyl)aminomethyl]benzimidazol-5-yl-carboxylic acid-N-cyclopentyl-N-(2-hydroxycarbonylethyl)amide

https://huagongshe.com/reaction/2227654

反応式

関与物質

役割名称HCID仕込み量
反応物Sodium HydroxideHCID 14798—
反応物1-Methyl-2-[N-(4-amidinophenyl)aminomethyl]benzimidazol-5-yl-carboxylic acid-N-cyclopentyl-N-(2-ethoxycarbonylethyl)amide HydrochlorideHCID 18412350—
生成物1-Methyl-2-[N-(4-amidinophenyl)aminomethyl]benzimidazol-5-yl-carboxylic acid-N-cyclopentyl-N-(2-hydroxycarbonylethyl)amideHCID 18412583—

反応手順

Prepared analogously to Example 26 from 1-methyl-2-[N-(4-amidinophenyl)aminomethyl]benzimidazol-5-yl-carboxylic acid-N-cyclopentyl-N-(2-ethoxycarbonylethyl)amide hydrochloride and sodium hydroxide solution.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US06414008B1
出典データセットuspto-grants-2002_07
ORD IDord-f62c69c079ee49908f304748fe685d33
出典メモuspto-grants-2002_07